Reducing HIV among 15–24-year-old adolescent girls and young women in Zambia through youth-friendly care and community support.

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Charles R. Drew University of Medicine and Science Zambia & Drew HealthCare Limited (Rise UP!) — Ministry of Health Zambia.

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About Us

Rise UP! Program Rise UP! in Zambia
Rise UP!

I. Rise UP! Overview

In October 2017, the Charles R. Drew University of Medicine and Science-LA (CDU-Los Angeles) team initiated a collaborative process with members of the Zambian Ministry of Health, the Medical Director of Chawama District Hospital (Dr. Shula Chanda), and other HIV specialists at Chawama Hospital to conduct a needs assessment of the Chawama catchment area. Out of this collaboration, the “Rise UP!” Project was born.

The overarching goal of Rise UP! is to reduce HIV infection rates among 15–24-year-old adolescent girls and young women (AGYW) in Zambia, a group that has been left behind as progress in reducing HIV in other groups has been achieved. By 2020, the Model scaled up to four General Level Hospitals in Lusaka—Chawama, Chilenje, Matero, and Kanyama. By 2021, it expanded to the Copperbelt with five sites: New Masala, Chipokota Mayamba, Buchi, Chimwemwe, and Ipusukilo.

Objectives of the Rise UP! Project

  • Reduce HIV infection rates among 15–24-year-old AGYW in Lusaka and Copperbelt by preventing new infections, ensuring adherence, and viral load suppression.
  • Facilitate empowerment and linkage to health services for AGYW.
  • Linkage to PrEP services in a private setting.
  • Capacity building for health facilities.

Youth-Friendly Services

PrEP & HIV Care

Overall Aim

Rise UP! team remains committed to strengthening the capacity of health care workers to address the psychosocial challenges adolescent and youths face during the developmental stages of adolescence to young adulthood and disproportionately affect them. The continued provision of life skills and psychosocial support services using our unique facility and community model has generated a reduction in vulnerabilities, risk-taking behaviour, and other consequences that they encounter.

Empowering Girls for a Better Tomorrow

Opportunity to Change Young Women's Lives

Through clinic- and community-based programming, we reach AGYW where they are—with prevention, testing, treatment, and peer support that builds trust and improves outcomes.

Reduce HIV infection rates among adolescents and youths in Zambia by preventing new infections, ensuring adherence to medication, and suppression of viral load.

Support life skills and psychosocial support services using our unique facility and community model has generated a reduction in vulnerabilities, risk-taking behavior, and other consequences that they encounter.

Over 4500+ AGYW have been enrolled to access primary care, treatment and continuity to healthcare.

Our Impact

Rise UP! – Making a Difference for AGYW in Zambia

PrEP

HIV Prevention & PrEP for AGYW

PrEP linkage and adherence support for at-risk AGYW in stigma-free settings.

11300 AGYW enrolled

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Care

HIV Care & Viral Load Suppression

Treatment linkage, retention, and psychosocial support through peer navigation and dedicated spaces.

5 Rise UP! Houses & 9 youth-friendly spaces

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Community

Community & Peer Navigation

Peer navigators, CBO partnerships, and community support to reach and retain AGYW.

Lusaka and Copperbelt provinces

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Our Approach

Why Rise UP!

Adolescent girls and young women (AGYW) in Zambia face a disproportionate HIV burden. Rise UP! addresses this through dedicated youth-friendly services, strong partnerships, and community-based care.

Youth-Friendly Spaces

Safe, welcoming environments for HIV testing, PrEP, and care without stigma—at nine sites.

PrEP & Prevention

Link HIV-negative AGYW to PrEP, STI testing, and counseling. Peer navigators and dedicated rooms support uptake and adherence.

Care & Retention

Treatment linkage, retention support, and viral load suppression through Houses and hospital partnerships.

4.9 ( Google Reviews)

"Rise UP! brings youth-friendly HIV prevention and care to adolescent girls and young women in Zambia. Whether it’s a local PrEP linkage, adherence support, and psychosocial services, we're making a real impact in Lusaka and Copperbelt."

4.9 ( Google Reviews)

"The partnership between CDU-Los Angeles (Charles R. Drew University of Medicine and Science-LA) and the Ministry of Health in Zambia has been essential to Rise UP!'s success. Whether it's a food distribution campaign or a clean water project, you’ll find plenty of ways to join hands with us. Check our upcoming events for details. We remain committed to safety, transparency, and community empowerment."

4.9 ( Google Reviews)

"Rise UP! Houses and youth-friendly spaces provide a safe, welcoming environment for AGYW to access HIV testing, PrEP, and care. Peer navigation and community support help retain young women in treatment."

4.9 ( Google Reviews)

"Reducing HIV among 15–24-year-old adolescent girls and young women is Rise UP!'s core goal. We prevent new infections, ensure adherence, and support viral load suppression through youth-friendly care."

Let’s Start Something For Them

Explore our impact and objectives.

Our Work
Partners & Collaboration

Built on Strong Partnerships

Rise UP! is a collaborative effort between U.S.-based academic institutions and Zambian health leadership, grounded in shared goals and local ownership.

Charles R. Drew University of Medicine and Science-LA (CDU-Los Angeles)

CDU-Los Angeles provides technical assistance, evaluation, and strategic support. Los Angeles–based staff travel to Zambia for site visits and participate in the HBCU Global Health Consortium to advance Rise UP! programming.

Ministry of Health, Zambia

The Ministry of Health provides national policy alignment, facility linkages, and operational support. Rise UP! works within government health systems to ensure sustainable, youth-friendly HIV services for AGYW.